Scalability =========== The scalability tutorial uses **single-process, in-memory, no-chunking** benchmarks. Each measured cell count is allocated and scored as one complete problem. This preserves the meaning of the benchmark and avoids presenting streamed partial calculations as an exact full-scale run. Two distinct workloads ---------------------- Cellwise DFFP metric transform ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Once selected-fate probabilities are available, CFA, DFR, FFS, RC, and UFP are cellwise operations with memory proportional to ``n_cells × n_fates``. The notebook includes an exact ladder whose target list extends to 200 million cells. A target is measured only when the current machine can allocate the complete arrays under the configured safety fraction. Full DFFP graph solve ~~~~~~~~~~~~~~~~~~~~~ The iterative DFFP solver stores the sparse transition graph plus at least one state-by-outcome probability matrix. Memory scales approximately with ``number of retained edges + n_cells × n_outcomes``. The notebook also benchmarks this complete sparse solve without partitioning. The exact target list includes 200 million cells, but a run is recorded as ``SKIPPED_INSUFFICIENT_MEMORY`` rather than silently chunked when the host cannot hold the full graph and solver state. Interpretation -------------- Measured runs, analytic memory estimates, and extrapolated times are reported in separate columns. A 200-million-cell claim is valid only when the row is marked ``MEASURED`` on the stated hardware, solver, graph degree, fate count, dtype, and tolerance. RNA-velocity preprocessing --------------------------- Neighbor construction, kinetic fitting, and velocity-graph estimation are outside the scCS scoring benchmark. They must be reported separately and should not be included in an scCS-only throughput claim. Plotting -------- Plotting may subsample cells because it is a rendering operation. Scientific scoring, probability propagation, population summaries, and inference are not subsampled in the no-chunk benchmark. High-memory exact 200-million-cell run -------------------------------------- The standard tutorial measures every complete problem that fits safely on the current host. To require the exact 200-million-cell full graph solve, run with ``SCCS_SCALABILITY_PROFILE=exact_200m``. The notebook raises an error if the complete allocation cannot be made. No chunked or out-of-core substitute is used. A degree-30 no-chunk ladder is reported separately from the degree-4 200-million-cell performance graph.